Master project: Scatter estimation for digital breast tomosynthesis

Contact: Pim Van Den Berg.

Scattered x-ray photons cause image blurring in digital mammography and breast tomosynthesis, see Figure 1. A solution is to estimate and remove scattered radiation with image processing. This can be done by simulating x-ray physics with slow and expensive Monte-Carlo methods. To improve performance, we have developed scatter predictors using deep neural networks by making use of our generative breast shape models, see Figure 2.

Figure 1: Example scatter radiation occuring during measurement. 

Picture2 Pim

Figure 2: Example of scatter analysis. Extracted from [1].

 

Method and tasks

Our state-of-the-art generative breast shape model has recently been extended to the technologically challenging medio-lateral oblique (MLO) view. We are also investigating image processing in more complex imaging modalities such as dual energy mammography. Your project will be centered around:

  • Adapting an existing scatter predictor to make use of our new MLO model.
  • Creating a new deep learning architecture to predict scattering as a function of x-ray energy (tube kV).

You will create the first real application of our new MLO breast shape model! This project involves working with 3D point clouds, neural networks and physics-based Monte-Carlo simulations in a Python environment.

Goals

  • A CC/MLO view agnostic scatter estimator.

  • A deep learning architecture for scatter estimation at any x-ray energy.

We are looking for a MSc student that is enthusiastic about:

  • Making a small but important advancement in breast cancer research
  • Applying physics-based simulations
  • Training and optimizing deep learning networks.

If you are interested, please contact our PhD student Pim van den Berg (This email address is being protected from spambots. You need JavaScript enabled to view it.) or postdoc Koen Michielsen (This email address is being protected from spambots. You need JavaScript enabled to view it.)! We are part of the Advanced X-ray Tomographic Imaging (AXTI) group at Radboud UMC.

The project duration is 6-9 months.

For more information, visit the research section associated with this project here.

References:

[1] Pinto MC et al. A deep learning approach to estimate x-ray scatter in digital breast tomosynthesis. Med Phys. 2023.

 

Tomographic Imaging

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