Imaging of pulmonary perfusion using subtraction CT angiography is feasible in clinical practice.

D. Grob, L. Oostven, M. Prokop, C.S. Prokop, I. Sechopoulos and M. Brink

Eur. Radiol. 2018



Subtraction computed tomography (SCT) is a technique that uses software-based motion correction between an unenhanced and an enhanced CT scan for obtaining the iodine distribution in the pulmonary parenchyma. This technique has been implemented in clinical practice for the evaluation of lung perfusion in CT pulmonary angiography (CTPA) in patients with suspicion of acute and chronic pulmonary embolism, with acceptable radiation dose. This paper discusses the technical principles, clinical interpretation, benefits and limitations of arterial subtraction CTPA.