Medical physics research at the Advanced X-ray Tomographic Imaging (AXTI, homophone of actie, meaning action in Dutch) lab focuses on radiation dosimetry, novel image acquisition and processing techniques, physical and perceptual evaluation of image quality, tomographic image reconstruction and advanced computational simulation methods in diagnostic x-ray based imaging, especially for breast and body tomographic imaging.
The aim of the AXTI lab is to perform state-of-the-art, clinically relevant research by working side by side with clinicians from the Department of Radiology and Nuclear Medicine at Radboudumc and collaborating with medical physicists and other scientists from around the world.
Our current projects involve the characterization and optimization of tomographic breast imaging methods, including breast tomosynthesis and dedicated breast CT. In addition, novel radiation dose metrics for personalized dosimetry in breast imaging are being developed. Research is also being performed on optimizing and characterizing the technical and clinical performance of functional chest and head CT.
AXTI is part of the “Women’s Cancers” research theme of the Radboud Institute for Health Sciences (RIHS). Our research is funded primarily by the National Institutes of Health of the USA and the Susan G. Komen Foundation for the Cure. The lab also works in collaboration with industry (Siemens Healthcare and Toshiba Medical Systems) and with the Dutch reference centre for screening (LRCB).