Digital breast tomosynthesis

Digital breast tomosynthesis (DBT) is an extension of conventional digital mammography (DM) that produces pseudo-three-dimensional reconstructed images of the breast from a set of low-dose x-ray projections acquired over a limited angular range. As a consequence, DBT can overcome the main limitation of DM: tissue superposition. The use of DBT in the clinical setting for breast cancer imaging is continuously growing throughout the world due to many studies indicating that DBT provides a higher sensitivity and specificity for breast cancer detection than DM. In addition, there are several large population-based screening trials that have proven that DBT should be regarded as a better mammogram, and considered as the new breast cancer screening technique for the near future. However, the potential of DBT is still undergoing a continuous evolution, with special focus in new reconstruction and processing techniques, synthetic mammograms, and acquisition protocols that can enhance its clinical performance, reduce radiation dose, and improve the image interpretation workflow.


Projects

Optimization and assessment of digital breast tomosynthesis
Optimization and assessment of digital breast tomosynthesis Digital breast tomosynthesis is undergoing a continuous evolution, with special focus in new acquisition protocols that can enhance its clinical performance, reduce radiation dose to the patients and improve reading workflow, More...
Optimizing quality control procedures in Digital Mammography and Digital Breast Tomosynthesis
Optimizing quality control procedures in Digital Mammography and Digital Breast Tomosynthesis Assessment of clinical image quality can be performed with human observers, such as medical physicists and radiologists, and with images of anthropomorphic phantoms or with clinical images. More...
Breast Shape Models
Breast Shape Models Many applications in breast imaging such as dosimetry models, x-ray scatter correction algorithms, and image processing techniques require realistic virtual breast models. We aim to provide objective models for use with these methods. More...
Quantitative Breast Tomosynthesis
Quantitative Breast Tomosynthesis Digital breast tomosynthesis (DBT) has rapidly been introduced for clinical use as an adjunct or replacement of mammography. Currently, most hospitals in the Netherlands use DBT for detection and diagnosis of breast cancer. More...
Image denoising and scatter modelling and correction
Image denoising and scatter modelling and correction In x-ray imaging, several factors can negatively affect the image quality and potentially hide an abnormality, first among all the image noise produced by the random photon distribution within the image, and the x-rays scattering. More...
Development of physical phantoms for breast dose quality control procedures
Development of physical phantoms for breast dose quality control procedures For evaluation of breast dosimetry in quality control (QC) procedures in digital mammography (DM) and digital breast tomosynthesis (DBT), a practical and reproducible method using phantoms is required. More...
Monte Carlo simulation for radiation dose evaluation and image system optimization
Monte Carlo simulation for radiation dose evaluation and image system optimization Monte Carlo (MC) computer simulations are a well-established methodology in diagnostic medical imaging research to estimate quantities that are challenging to be measured empirically, such as the radiation dose or the amount of scatter radiation. More...